"The most important thing in science is to be together with a colleague at that moment when you discover something. When some little piece of nature unfolds and you see something new. "
"Suppose you lived in a world in which the ground was a crossword puzzle. Would you or would you not try to solve the puzzle?""
"I would like to try and impress upon you while I am talking about all of these things on a small scale, the importance of improving the electron microscope by a hundred times. It is not impossible; it is not against the laws of diffraction of the electron. The wave length of the electron in such a microscope is only 1/20 of an angstrom. So it should be possible to see the individual atoms. "
"People had theoretically showed it could be done, but no one thought the instrument was practical. Theory showed that if you had enough electrons hitting a specimen to achieve the magnification you needed, you would burn the specimen."
"“resolution is clearly limited by the unavailability of the necessary funds”. "
"We were bombarded — this is the best way to put it — by requests from all the medical people and all the colloidal physics people — everybody that had things too small to be seen in a light microscope. We quickly realized that two graduate students working in a makeshift lab with a makeshift instrument couldn't satisfy the needs for this tool. "
"Its pictures had for me the effect of the song of a mermaid: irresistible and half transparent."