"I didn't know enough diffraction theory to even know why what I was doing wouldn't work. That was a problem. I was too much of an empiricist at the time. I learned later that it's better to know what you are doing."
"Our century has seen the creation of new means of doing research. In particular, the electron microscope and chemical and biochemical methods of analysis have revolutionized our knowledge of the foundations of life..."
"We were bombarded — this is the best way to put it — by requests from all the medical people and all the colloidal physics people — everybody that had things too small to be seen in a light microscope. We quickly realized that two graduate students working in a makeshift lab with a makeshift instrument couldn't satisfy the needs for this tool. "
"The standard doesn't explain why you need a four letter acronym for three words. I think it just makes it sound more important."
"There was no physical law to prevent it."
"... fluorescence microscopy in its early years was considered a specialized method which, in the opinion of some, was doomed to fail. "
"It took me about twenty years before I had the right system that could be realized in practice and that scientist said it could work"
"I thought that if I patented it, no one else would be able to do work with it. I might earn some money, but I was not interested in that. I was interested in applications for many researchers, creating more fundamental science. So I decided not to patent it."