"Our century has seen the creation of new means of doing research. In particular, the electron microscope and chemical and biochemical methods of analysis have revolutionized our knowledge of the foundations of life..."
"One day I was testing my instrument and with my own eyes, for the first time in the world, I saw atoms working in a chemical reaction, changing their atomic structure, and it was absolutely thrilling."
"I was half asleep, thinking, 'How the heck can you stretch a magnetic field to straighten it up, to make it really circular, instead of slightly elliptical?' "
"I thought that if I patented it, no one else would be able to do work with it. I might earn some money, but I was not interested in that. I was interested in applications for many researchers, creating more fundamental science. So I decided not to patent it."
"People had theoretically showed it could be done, but no one thought the instrument was practical. Theory showed that if you had enough electrons hitting a specimen to achieve the magnification you needed, you would burn the specimen."
"I believe that you have to take some intelligent risks to advance science."
"Cell Biology finally makes possible a century old dream: that of analysis of diseases, at the cellular level - the first step towards their final control."
"From now on, we work with positive tip voltage."