"We were bombarded — this is the best way to put it — by requests from all the medical people and all the colloidal physics people — everybody that had things too small to be seen in a light microscope. We quickly realized that two graduate students working in a makeshift lab with a makeshift instrument couldn't satisfy the needs for this tool. "
"...a lot of people will advise you. On the one hand you want to listen, and on the other hand you want to test it and say, ‘Okay, is this really making sense, or is it just that somebody I really respect said this?’”"
"Its pictures had for me the effect of the song of a mermaid: irresistible and half transparent."
"The interesting basic questions in that field are extremely hard and may never be answered, and to survive as a scientist you have to work on answerable questions."
"We replaced the wave length of the light by the wave length of electrons at an accelerating voltage of 75 kV and inserted into the Abbe relation the imaging accelerating voltage of 75 kV and inserted into the Abbe relation the imaging accelerating voltage of 75 kV and inserted into the Abbe relation the imaging aperture of 2 X 10-2 rad...we came up with a resolution limit of 2.2 Å ."
"I believe that you have to take some intelligent risks to advance science."
"Scientific inquiry starts with observation. The more one can see, the more one can investigate. Indeed, we often mark our progress in science by improvements in imaging. "