"The electron microscope is like the monkey wrench on the garage wall; what you do with it is the important thing."
"... fluorescence microscopy in its early years was considered a specialized method which, in the opinion of some, was doomed to fail. "
"A project for a Ph.D. student must provide him with good training and, if he is doing experimental work, there is much to be said for choosing a problem which involves the construction or modification of some fairly complicated apparatus. I have always felt that university research in engineering should be adventurous and should not mind tackling speculative projects"
"From now on, we work with positive tip voltage."
"It is my intention to offer a prize of $1,000 to the first guy who can take the information on the page of a book and put it on an area 1/25,000 smaller in linear scale in such manner that it can be read by an electron microscope. "
"Roger, at Cornell University they have an incredible piece of scientific equipment known as the Tunneling Electron Microscope. Now, this microscope is so powerful that by firing electrons you can actually see images of the atom, the infinitesimally minute building blocks of our universe. Roger, if I were using that microscope right now, I still wouldn't be able to locate my interest in your problem. "
"I didn't know enough diffraction theory to even know why what I was doing wouldn't work. That was a problem. I was too much of an empiricist at the time. I learned later that it's better to know what you are doing."
"You can observe a lot by watching."