ORNL microscopy directly images lithium dendrites in batteries Learn more...
Microscopy Products, News, Events and Resources
Is a resolution of 0. 1 Å for electron microscopes possible and if so is it a goal worthy of pursuit. Stephen Pennycook and Sergei Kalinin weigh in on this question Microscopy: Hasten high resolution. Learn more... Image: Wu Zhou/Oak Ridge Natl Lab
Multi-layer Laue lens module inside the vacuum chamber of the microscope installed at the Hard X-ray Nanoprobe beamline at NSLS-II. Learn more...
Using cryo-electron microscopy researchers at Berkeley Labs captured images of bacteria that are at the lower size limit for life. Learn more...
Obtaining EBSD patterns from 10 nanometer crystals can be done with modifications to standard SEM EBSD systems. Learn more... Image: Roy Geiss, NIST
A new technique using stimulated Raman scattering (SRS) microscopy and metabolic labeling images new synthesized protein in live cells. Learn more... Lu Wei of Columbia University
Barnacle appendages. Confocal microscopy, Igor Siwanowicz, HHMI Janelia Research Campus. One of many stunning images from the galleries from the Olympus BioScapes Digital Imaging Competition®. Learn more...
SCAPE High-Speed 3D Microscope imaging of the living brain, with green GCaMP labeling apical dendrites of layer 5 neurons, and red showing Texas red dextran in the vasculature. Learn more... Image: Elizabeth Hillman and Clay Lacefield
Our mission is to find the most interesting news on advancements in microscope instrumentation and the discoveries made using microscopy to you. News from academic and government research labs, manufacturers, and societies are included.
Research and Innovations
Transient Absorption (TA) Microscopy couples ultrafast temporal resolution with high spatial resolution to obtain information on heterogeneous electronic properties across domains ranging from tens to hundreds of nanometers in size of organic photovoltaic films. The technique measures changes in adsorption spectra resulting from femtosecond laser pulses that have excited the transient energy states.
John Miao, a UCLA professor, and his colleagues have contributed an article to the May 2015 issue of Science, in which they review and analyze the wide range of applications that have stemmed from Miao's technique of coherent diffractive imaging (CDI). Developed in 1999, CDI uses an X-ray and a computational algorithm to interpret the diffraction pattern, instead of a lens. This allows users to achieve high-resolution, high-contrast imaging of nanoscale objects, and was the first method in X-ray crystallography to enable imaging of noncrystalline materials and nanocrystals.
The National Physical Laboratory (NPL) has developed a microscopic specimen that features single-nanometer spacings. These protein nanostructures would make an excellent material for calibration standards. EM users would be able to calibrate with greater reproducibility, accuracy, traceability and precision.
The Korea Advanced Institute of Science and Technology (KAIST) has published an article in Optics Express, the journal of the The Optical Society detailing a new microscope technique to identify bacteria more quickly. This simple modification to a traditional microscope could help in medical applications by eliminating the need to culture microbes prior to identification, and in food services applications to identify any pathogens. It works by using laser holographic techniques to identify single bacterial species, and uses mathematical and computer software with a machine-learning algorithm that is similar to that used for facial recognition in security cameras.
Product and Company
Hitachi High-Technologies Corporation will introduce its new instrument, the NX9000, at Microscopy & Microanalysis 2015 in Portland, U.S.A. from August 2-6, 2015. The NX9000 is the second product created through the collaboration of Hitachi High-Tech and its subsidiary Hitachi High-Tech Science Corporation. This real-time 3D analytical FIB*1-SEM*2 composite instrument boasts improved 3D structural analysis precision and throughput, and can be used in applications of SEM observation, 3D EBSD, 3D EDS, TEM or atom probe sample preparation, and more. By arranging the SEM column and FIB column orthogonally, instead of diagonally, the NX9000 is optimized for improved throughput and precision in 3D structural analysis applications.
Bruker has launched the OPTIMUS™ TKD detector head for use with scanning electron microscope. The head can be easily interchanged with Bruker e-Flash EBSD detectors, so users have access to Transmission Kikuchi Diffraction (TKD) and EBSD with the same detector. OPTIMUS™ TKD provides a simple, cost-effective method of obtaining Selected Area Electron Diffraction (SAED) patterns like those acquired through TEM, and can be integrated with the ARGUS™ direct electron detection system to allow for bright field and dark field images.
Leica Microsystems has launched the Leica DM2500 LED, completing the Leica DM1000 to 3000 series of microscopes. All the microscopes are available with an LED illumination feature, which keeps a constant color temperature. The DM2500 LED can be used for demanding applications in clinical labs, and research applications in cytology, developmental biology, microbiology, botany, and zoology, to name a few.
Quotes / About Microscopy and From Microscopists
"The electron microscope is like the monkey wrench on the garage wall; what you do with it is the important thing."
"I didn't know enough diffraction theory to even know why what I was doing wouldn't work. That was a problem. I was too much of an empiricist at the time. I learned later that it's better to know what you are doing."
"Scientific inquiry starts with observation. The more one can see, the more one can investigate. Indeed, we often mark our progress in science by improvements in imaging. "
"It took me about twenty years before I had the right system that could be realized in practice and that scientist said it could work"