ORNL microscopy directly images lithium dendrites in batteries Learn more...
Microscopy Products, News, Events and Resources
Is a resolution of 0. 1 Å for electron microscopes possible and if so is it a goal worthy of pursuit. Stephen Pennycook and Sergei Kalinin weigh in on this question Microscopy: Hasten high resolution. Learn more... Image: Wu Zhou/Oak Ridge Natl Lab
Multi-layer Laue lens module inside the vacuum chamber of the microscope installed at the Hard X-ray Nanoprobe beamline at NSLS-II. Learn more...
Using cryo-electron microscopy researchers at Berkeley Labs captured images of bacteria that are at the lower size limit for life. Learn more...
A new technique using stimulated Raman scattering (SRS) microscopy and metabolic labeling images new synthesized protein in live cells. Learn more... Lu Wei of Columbia University
Barnacle appendages. Confocal microscopy, Igor Siwanowicz, HHMI Janelia Research Campus. One of many stunning images from the galleries from the Olympus BioScapes Digital Imaging Competition®. Learn more...
SCAPE High-Speed 3D Microscope imaging of the living brain, with green GCaMP labeling apical dendrites of layer 5 neurons, and red showing Texas red dextran in the vasculature. Learn more... Image: Elizabeth Hillman and Clay Lacefield
Our mission is to find the most interesting news on advancements in microscope instrumentation and the discoveries made using microscopy to you. News from academic and government research labs, manufacturers, and societies are included.
Research and Innovations
The Astbury Centre for Structural Molecular Biology at the University of Leeds in the United Kingdom has purchased two Titan Krios™ cryo transmission electron microscopes (cryo-TEMs) from FEI. The microscopes will be installed in a renovated facility in March of 2016.
Cryo-electron microscopy has revealed the atomic structure of the Bluetongue virus and has revealed how how the virus infects healthy cells. This understanding of the disease that has killed millions of cattle will aid in the develop of vaccines and treatments.
The $1.83 million three-year grant, part of the White House’s Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative, will support her work on SCAPE, a high-speed 3D microscope that she has developed for imaging the living brain.
Two FEI Titan Krios cryo transmission electron microscopes (TEMs), a Scios DualBeam focused ion beam/scanning electron microscope (FIB/SEM), and a Talos cryo-TEM have been ordered by Diamond Light Source for the electron biology facility (EBIC).
Product and Company
Heptares Therapeutics has joined the Cambridge-Pharmaceutical Cryo-EM Consortium which will evaluate the potential of cryo-electron microscopy (cryo-EM) for determining three-dimensional (3D) information about protein structures at the molecular level.
Hitachi High-Technologies Corporation will introduce its new instrument, the NX9000, at Microscopy & Microanalysis 2015 in Portland, U.S.A. from August 2-6, 2015. The NX9000 is the second product created through the collaboration of Hitachi High-Tech and its subsidiary Hitachi High-Tech Science Corporation. This real-time 3D analytical FIB*1-SEM*2 composite instrument boasts improved 3D structural analysis precision and throughput, and can be used in applications of SEM observation, 3D EBSD, 3D EDS, TEM or atom probe sample preparation, and more. By arranging the SEM column and FIB column orthogonally, instead of diagonally, the NX9000 is optimized for improved throughput and precision in 3D structural analysis applications.
Bruker has launched the OPTIMUS™ TKD detector head for use with scanning electron microscope. The head can be easily interchanged with Bruker e-Flash EBSD detectors, so users have access to Transmission Kikuchi Diffraction (TKD) and EBSD with the same detector. OPTIMUS™ TKD provides a simple, cost-effective method of obtaining Selected Area Electron Diffraction (SAED) patterns like those acquired through TEM, and can be integrated with the ARGUS™ direct electron detection system to allow for bright field and dark field images.
Quotes / About Microscopy and From Microscopists
"...a lot of people will advise you. On the one hand you want to listen, and on the other hand you want to test it and say, ‘Okay, is this really making sense, or is it just that somebody I really respect said this?’”"
"Scanning electron microscopy: Second best no more."
"I didn't know enough diffraction theory to even know why what I was doing wouldn't work. That was a problem. I was too much of an empiricist at the time. I learned later that it's better to know what you are doing."
"We replaced the wave length of the light by the wave length of electrons at an accelerating voltage of 75 kV and inserted into the Abbe relation the imaging accelerating voltage of 75 kV and inserted into the Abbe relation the imaging accelerating voltage of 75 kV and inserted into the Abbe relation the imaging aperture of 2 X 10-2 rad...we came up with a resolution limit of 2.2 Å ."